Anthracyclines

AnthracyclinesTBD-Biodiscovery is good at total synthesis with the step-by-step polycycle and side-chain construction and the following modifications. We have also modified anthracyclines accessible by fermentation and synthesised for example Amrubicin, Amurubicinone, Nemorubicin, Doxorubicin, Ԑ-rhodomycinone and different metabolites.

PNU-159682

  • Metabolite of Nemorubicin
  • Mechanism of action: intercalation with DNA
  • 1000 times more potent that Doxorubicin
  • Purity: 95% (HPLC)
  • Quantities: in grams
  • Conjugates