Services

TBD-Biodiscovery provides top class services to biotech and pharma industry. Our services include contract research, analytics, process development and GMP-certified manufacturing.

The company contributes to modern anti-cancer drug development, innovative diagnostics methods and smart solutions for chemical and agrochemical industry.

OUR CORE SERVICES:

COMPLEX CHEMICAL SYNTHESIS

  • Literature searches and analysis including route-mapping
  • Patent searches
  • Route-scouting of drug candidates
  • Total synthesis up to 30 steps
  • Feasibility studies
  • Scale-up to kilo scale
  • Process optimization using Design of Experiments approach

ANALYTICAL LABORATORY SERVICES

  • Methods development and validation
  • Impurities (isolation and qualification)
  • Stability studies and tests for final drug forms
  • Please see more HERE!

API PRODUCT DEVELOPMENT

  • Process validation and ASMF compilation
  • Analytical development and impurity synthesis
  • Please see more HERE!

PRODUCTION OF PAYLOADS FOR ANTIBODY-DRUG CANDIDATES

  • Custom synthesis and GMP-certified production of payloads
  • Conjugation services
  • Please see more HERE!

EXPERTISE IN CHEMISTRY

  • Peptidomimetics and oligopeptidomimetics: toxins for ADC. 20-30 step synthesis, construction and coupling of the building blocks, separation of diastereomers, development of purification methods
  • Anthracyclines:  total synthesis with step-by-step construction of polycycle and side-chains with following modifications
  • Peptide linkers
  • Pheromones and their derivatives: Lobesia botrana, Cydia pomonella etc.
  • Near – IR dyes
  • Fluorescent labeled molecules (dd-modified nucleotides for DNA-array analysis) and labels for biomolecules (e.g. FLAsH analogues)

……………the list is never full, so please do not hesitate to contact us.