TBD-Biodiscovery is good at total synthesis with the step-by-step polycycle and side-chain construction and the following modifications. We have also modified anthracyclines accessible by fermentation and synthesised for example Amrubicin, Amurubicinone, Nemorubicin, Doxorubicin, Ԑ-rhodomycinone and different metabolites.
- Metabolite of Nemorubicin
- Mechanism of action: intercalation with DNA
- 1000 times more potent that Doxorubicin
- Purity: 95% (HPLC)
- Quantities: in grams