(S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid, Firefly Luciferin (synthetic)
Quantity: from milligrams to kilos
- Appearance: white
- Color of solution: colorless to light yellow
- Identity (NMR): complies
- Purity (HPLC): 99+%
- Chiral purity (HPLC): 99+%
- Biological performance: >99%
D-Luciferin is a chemical substance found in cells of various bioluminescent organisms. The ATP-dependent oxidation of Luciferin by luciferase produces light, and this system is employed as a reporter in plants, bacteria, and mammalian cells. D-Luciferin Potassium or Sodium salt has significantly better solubility in water than D-Luciferin free acid, thus being an excellent choice for experiments in higher concentrations.
D-Luciferin is a common reagent used throughout the biotechnology field and particularly for in vivo imaging. Luciferase labeled tumor cells, stem cells, or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of D-Luciferin allows for the real-time, non-invasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).
TBD-Biodiscovery produces both D-Luciferin and D-Luciferin Potassium/Sodium salts.